From mensvariety.com…

Truvada was the original PrEP drug. All of the trials and data about PrEP that you can find right now are about Truvada. It’s the tried and true option. Meanwhile, the Food and Drug Administration approved a second drug in 2019 from Gilead Sciences. As clinic trials showed, this second drug, called Descovy, is less toxic to the kidneys and bones than Truvada. That’s not to say that Truvada is toxic, but that the drug can possibly cause kidney problems or bone mineral density problems later on. As such, PrEP users have celebrated the arrival of Descovy. On top of that, it is MORE effective in preventing HIV. But, of course, it’s more expensive too.

Are you considering getting PrEP but need to know more basic info before you take the plunge? Are you concerned about your safe sex measures and want to know your options in protecting yourself from STIs like HIV? We decided it would be a good idea to write up a “basics” post and general guide for anyone wanting to know more about the HIV-preventive drug. If that sounds interesting to you, keep reading…